2024 ICD-10-CM Diagnosis Code C21.1

Malignant neoplasm of anal canal

  • C21.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM C21.1 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C21.1 – other international versions of ICD-10 C21.1 may differ.

Applicable To

  • Malignant neoplasm of anal sphincter

The following code(s) above C21.1 contain annotation back-references

 that may be applicable to C21.1:

  • C00-D49  Neoplasms
  • C15-C26  Malignant neoplasms of digestive organs
  • C21  Malignant neoplasm of anus and anal canal

Approximate Synonyms

  • Cancer of the anal canal
  • Primary malignant neoplasm of anal canal
  • Primary squamous cell carcinoma of anal canal
  • Squamous cell carcinoma, anal canal

ICD-10-CM C21.1 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 374 Digestive malignancy with mcc
  • 375 Digestive malignancy with cc
  • 376 Digestive malignancy without cc/mcc

Convert C21.1 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change