2025 ICD-10-CM Diagnosis Code I48.21

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Permanent atrial fibrillation

  • I48.21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2025 edition of ICD-10-CM I48.21 became effective on October 1, 2024.
  • This is the American ICD-10-CM version of I48.21 – other international versions of ICD-10 I48.21 may differ.

The following code(s) above I48.21 contain annotation back-references

 that may be applicable to I48.21:

  • I00-I99  Diseases of the circulatory system

ICD-10-CM I48.21 is grouped within Diagnostic Related Group(s) (MS-DRG v42.0):

  • 308 Cardiac arrhythmia and conduction disorders with mcc
  • 309 Cardiac arrhythmia and conduction disorders with cc
  • 310 Cardiac arrhythmia and conduction disorders without cc/mcc
  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems

Code History

  • 2020 (effective 10/1/2019): New code
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Code annotations containing back-references to I48.21:

  • Type 1 Excludes: I48.1

Diagnosis Index entries containing back-references to I48.21:

  • Fibrillation
    • atrial or auricular (established) I48.91
      • permanent I48.21
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