2024 ICD-10-CM Diagnosis Code C58

by

Malignant neoplasm of placenta

  • C58 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM C58 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C58 – other international versions of ICD-10 C58 may differ.

ICD-10-CM Coding Rules

  • C58 is applicable to maternity patients aged 12 – 55 years inclusive.
  • C58 is applicable to female patients.

Type 1 Excludes

  • chorioadenoma (destruens) (D39.2)
  • hydatidiform mole NOS (O01.9)
  • invasive hydatidiform mole (D39.2)
  • male choriocarcinoma NOS (C62.9-)
  • malignant hydatidiform mole (D39.2)

Includes

  • choriocarcinoma NOS
  • chorionepithelioma NOS

The following code(s) above C58 contain annotation back-references

 that may be applicable to C58:

  • C00-D49  Neoplasms
  • C51-C58  Malignant neoplasms of female genital organs

Approximate Synonyms

  • Cancer of the placenta
  • Cancer of the placenta, choriocarcinoma
  • Choriocarcinoma
  • Female choriocarcinoma
  • Gestational choriocarcinoma
  • Gestational trophoblastic neoplasia
  • Primary malignant neoplasm of placenta

Clinical Information

  • A malignant metastatic form of trophoblastic tumors. Unlike the hydatidiform mole, choriocarcinoma contains no chorionic villi but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (trophoblasts). It is characterized by the large amounts of chorionic gonadotropin produced. Tissue origins can be determined by dna analyses: placental (fetal) origin or non-placental origin (choriocarcinoma, non-gestational).
  • A malignant neoplasm arising from decidua (placental) cells.
  • A malignant neoplasm arising from placental trophoblast cells. They generally arise in the uterus.
  • A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease.
  • An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hcg) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.
  • Malignant metastatic form of trophoblastic tumors, contains sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts; characterized by the large amounts of chorionic gonadotropin produced; tissue origins can be placental (fetal) or non-placental.
  • Malignant neoplasm originating in the placenta

ICD-10-CM C58 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 736 Uterine and adnexa procedures for ovarian or adnexal malignancy with mcc
  • 737 Uterine and adnexa procedures for ovarian or adnexal malignancy with cc
  • 738 Uterine and adnexa procedures for ovarian or adnexal malignancy without cc/mcc
  • 739 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with mcc
  • 740 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with cc
  • 741 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy without cc/mcc
  • 754 Malignancy, female reproductive system with mcc
  • 755 Malignancy, female reproductive system with cc
  • 756 Malignancy, female reproductive system without cc/mcc

Convert C58 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Diagnosis Index entries containing back-references to C58: