2024 ICD-10-CM Diagnosis Code C52

Malignant neoplasm of vagina

  • C52 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM C52 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C52 – other international versions of ICD-10 C52 may differ.

ICD-10-CM Coding Rules

  • C52 is applicable to female patients.

Type 1 Excludes

  • carcinoma in situ of vagina (D07.2)

The following code(s) above C52 contain annotation back-references

 that may be applicable to C52:

  • C00-D49  Neoplasms
  • C51-C58  Malignant neoplasms of female genital organs

Approximate Synonyms

  • Cancer of the vagina, adenocarcinoma
  • Cancer of the vagina, primary
  • Cancer of the vagina, recurrent to primary site
  • Cancer of the vagina, squamous cell
  • Malignant melanoma of vagina
  • Melanoma, vagina
  • Primary adenocarcinoma of vagina
  • Primary malignant neoplasm of vagina
  • Recurrent primary malignant neoplasm of vagina
  • Squamous cell cancer of vagina

Clinical Information

  • A primary or metastatic malignant tumor involving the vagina. Representative examples include carcinomas and sarcomas.
  • Vaginal cancer is a rare type of cancer. It is more common in women 60 and older. You are also more likely to get it if you have a human papillomavirus (hpv) infection or if your mother took diethylstilbestrol (des) when she was pregnant. Doctors prescribed des in the 1950’s to prevent miscarriages.it often doesn’t have early symptoms. However, see your doctor if you notice
    • bleeding that is not your period
    • a vaginal lump
    • pelvic pain
    a pap test can find abnormal cells that may be cancer. Vaginal cancer can often be cured in its early stages. Treatment might include surgery, radiation and chemotherapy. nih: national cancer institute

ICD-10-CM C52 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 736 Uterine and adnexa procedures for ovarian or adnexal malignancy with mcc
  • 737 Uterine and adnexa procedures for ovarian or adnexal malignancy with cc
  • 738 Uterine and adnexa procedures for ovarian or adnexal malignancy without cc/mcc
  • 739 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with mcc
  • 740 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy with cc
  • 741 Uterine and adnexa procedures for non-ovarian and non-adnexal malignancy without cc/mcc
  • 754 Malignancy, female reproductive system with mcc
  • 755 Malignancy, female reproductive system with cc
  • 756 Malignancy, female reproductive system without cc/mcc

Convert C52 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change