2024 ICD-10-CM Diagnosis Code C50

by

Malignant neoplasm of breast

  • C50 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2024 edition of ICD-10-CM C50 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C50 – other international versions of ICD-10 C50 may differ.

Use Additional

  • code to identify estrogen receptor status (Z17.0, Z17.1)

Type 1 Excludes

  • skin of breast (C44.501, C44.511, C44.521, C44.591)

Includes

  • connective tissue of breast
  • Paget’s disease of breast
  • Paget’s disease of nipple

The following code(s) above C50 contain annotation back-references

 that may be applicable to C50:

Clinical Information

  • A form of breast cancer in which the tumor grows from ducts beneath the nipple onto the surface of the nipple. Symptoms commonly include itching and burning and an eczema-like condition around the nipple, sometimes accompanied by oozing or bleeding.
  • A malignant epithelial cellular proliferation characterized by the presence of atypical cells with large nuclei and abundant pale cytoplasm within the squamous epithelium of the nipple. In almost all cases there is an underlying intraductal breast carcinoma or intraductal and invasive carcinoma. The skin changes range from redness to eczematous appearance.
  • A malignant neoplasm in which there is infiltration of the skin overlying the breast by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (paget cells). It is almost always associated with an intraductal or invasive ductal carcinoma of the breast. The clinical features include focal skin reddening, and eczema. Retraction of the nipple may sometimes occur.
  • A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males.
  • An intraductal carcinoma of the breast extending to involve the nipple and areola, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (paget’s cells). (Dorland, 27th ed)
  • Breast cancer affects one in eight women during their lives. Breast cancer kills more women in the United States than any cancer except lung cancer. No one knows why some women get breast cancer, but there are a number of risk factors. Risks that you cannot change include
    • age – the chance of getting breast cancer rises as a woman gets older
    • genes – there are two genes, brca1 and brca2, that greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested.
    • personal factors – beginning periods before age 12 or going through menopause after age 55
    other risks include being overweight, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35 or having dense breasts.symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast or discharge from a nipple. Breast self-exam and mammography can help find breast cancer early when it is most treatable. Treatment may consist of radiation, lumpectomy, mastectomy, chemotherapy and hormone therapy.men can have breast cancer, too, but the number of cases is small. nih: national cancer institute
  • Carcinoma of the breast extending to involve the nipple and areola, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells.

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to C50:

  • Code Also: D61.82
  • Code First: D75.81, Z17, Z79.81
  • Type 1 Excludes: C49, C49.3, D05
  • Applicable To: Z80.3, Z85.3