2024 ICD-10-CM Diagnosis Code C45.2

Mesothelioma of pericardium

  • C45.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM C45.2 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C45.2 – other international versions of ICD-10 C45.2 may differ.

Type 1 Excludes

  • other malignant neoplasm of pericardium (C38.0)

The following code(s) above C45.2 contain annotation back-references

 that may be applicable to C45.2:

Approximate Synonyms

  • Malignant mesothelioma of pericardium
  • Malignant mesothelioma, pericardium

Clinical Information

  • This is a rare tumor. Approximately 100 to 150 cases have been reported in the literature. In most cases the diagnosis is made at autopsy or postoperatively. Clinical signs and symptoms include: pericardial effusion, congestive heart failure, a mass or tamponade. The prognosis for pericardial mesothelioma is extremely poor due to its late presentation and difficulty in completely removing it surgically. Surgical resection remains the treatment of choice. Addition of chemotherapy or radiation have been disappointing.

ICD-10-CM C45.2 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 314 Other circulatory system diagnoses with mcc
  • 315 Other circulatory system diagnoses with cc
  • 316 Other circulatory system diagnoses without cc/mcc

Convert C45.2 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Diagnosis Index entries containing back-references to C45.2: