2024 ICD-10-CM Diagnosis Code C45

Mesothelioma

  • C45 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2024 edition of ICD-10-CM C45 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C45 – other international versions of ICD-10 C45 may differ.

The following code(s) above C45 contain annotation back-references

 that may be applicable to C45:

Clinical Information

  • A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma.
  • A benign or malignant tumor affecting the lining of the chest or abdomen
  • A neoplasm originating from mesothelial cells of the pleura or peritoneum, for which the malignancy status has not been established.
  • A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
  • A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
  • Malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium.
  • The tissue that lines your lungs, stomach, heart and other organs is called mesothelium. Mesothelioma is cancer of that tissue. It is a rare but serious type of cancer. It usually starts in the lungs, but can also start in the abdomen or other organs. Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles. It can take a long time – 30 to 50 years – between being around asbestos and getting the disease. Treatment includes surgery, radiation, chemotherapy or all three. nih: national cancer institute

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to C45:

  • Type 1 Excludes: C38C48
  • Type 2 Excludes: C49