2024 ICD-10-CM Diagnosis Code C25

Malignant neoplasm of pancreas

  • C25 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.
  • The 2024 edition of ICD-10-CM C25 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of C25 – other international versions of ICD-10 C25 may differ.

Use Additional

  • code to identify:
  • alcohol abuse and dependence (F10.-)

Code Also

  • if applicable exocrine pancreatic insufficiency (K86.81)

The following code(s) above C25 contain annotation back-references

 that may be applicable to C25:

  • C00-D49  Neoplasms
  • C15-C26  Malignant neoplasms of digestive organs

Clinical Information

  • A primary or metastatic malignant tumor involving the pancreas. Representative examples include carcinoma and lymphoma.
  • The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Cancer of the pancreas is the fourth-leading cause of cancer death in the United States Some risk factors for developing pancreatic cancer include
    • smoking
    • long-term diabetes
    • chronic pancreatitis
    • certain hereditary disorders
    pancreatic cancer is hard to catch early. It doesn’t cause symptoms right away. When you do get symptoms, they are often vague or you may not notice them. They include yellowing of the skin and eyes, pain in the abdomen and back, weight loss and fatigue. Also, because the pancreas is hidden behind other organs, health care providers cannot see or feel the tumors during routine exams. Because it is often found late and it spreads quickly, pancreatic cancer can be hard to treat. Possible treatments include surgery, radiation and chemotherapy. nih: national cancer institute

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to C25:

Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

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