2024 ICD-10-CM Diagnosis Code A52.3

by

Neurosyphilis, unspecified

  • A52.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM A52.3 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of A52.3 – other international versions of ICD-10 A52.3 may differ.

Applicable To

  • Gumma (syphilitic)
  • Syphilis (late)
  • Syphiloma

The following code(s) above A52.3 contain annotation back-references

 that may be applicable to A52.3:

  • A00-B99  Certain infectious and parasitic diseases
  • A50-A64  Infections with a predominantly sexual mode of transmission

Approximate Synonyms

  • Neurosyphilis

Clinical Information

  • Infection of the brain or spinal cord by treponema pallidum. It occurs many years following the original infection which remained untreated. Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia.
  • Infections of the central nervous system caused by treponema pallidum which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as brain infarction. The infection may also remain subclinical for several years. Late syndromes include general paresis; tabes dorsalis; meningeal syphilis; syphilitic optic atrophy; and spinal syphilis. General paresis is characterized by progressive dementia; dysarthria; tremor; myoclonus; seizures; and argyll-robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)

ICD-10-CM A52.3 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 056 Degenerative nervous system disorders with mcc
  • 057 Degenerative nervous system disorders without mcc

Convert A52.3 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Diagnosis Index entries containing back-references to A52.3: