2024 ICD-10-CM Diagnosis Code A48.3

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Toxic shock syndrome

  • A48.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM A48.3 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of A48.3 – other international versions of ICD-10 A48.3 may differ.

Use Additional

  • code to identify the organism (B95, B96)

Type 1 Excludes

The following code(s) above A48.3 contain annotation back-references

 that may be applicable to A48.3:

  • A00-B99  Certain infectious and parasitic diseases
  • A48  Other bacterial diseases, not elsewhere classified

Approximate Synonyms

  • Staphylococcal toxic shock syndrome
  • Toxic shock syndrome due to methicillin resistant staphylococcus aureus infection
  • Toxic shock syndrome due to methicillin susceptible staphylococcus aureus
  • Toxic shock syndrome due to mrsa
  • Toxic shock syndrome due to staphylococcus

Clinical Information

  • A fatal disease caused by an infection
  • A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. Tss characterised by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings consistent with tss include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.
  • A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. Tss characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings consistent with tss include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.
  • A severe illness caused by infection with staphylococcus aureus and characterized by high fever of sudden onset, vomiting, diarrhea, and myalgia, followed by hypotension and in severe cases, shock; a sunburn-like rash with peeling of the skin, especially of the palms and soles, occurs during the acute phase.
  • Syndrome characterized by high fever, vomiting, diarrhea, confusion, and skin rash; almost all cases have been related to an infection with toxin-producing staphylococcus aureus.

ICD-10-CM A48.3 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 867 Other infectious and parasitic diseases diagnoses with mcc
  • 868 Other infectious and parasitic diseases diagnoses with cc
  • 869 Other infectious and parasitic diseases diagnoses without cc/mcc

Convert A48.3 to ICD-9-CMCode History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to A48.3:

  • Type 1 Excludes: R57
  • Type 2 Excludes: A41

Diagnosis Index entries containing back-references to A48.3: